Exceptional diversity, maintenance of polymorphism, and recent directional selection on the APL1 malaria resistance genes of Anopheles gambiae.

Exceptional diversity, maintenance of polymorphism, and recent directional selection on the APL1 malaria resistance genes of Anopheles gambiae.

The three-gene APL1 locus encodes essential components of the mosquito immune defense against malaria parasites. APL1 was originally identified because it lies within a mapped QTL conferring the vector mosquito Anopheles gambiae natural resistance to the human malaria parasite, Plasmodium falciparum...

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Bibliographic Details
Main Authors: Susan M Rottschaefer, Michelle M Riehle, Boubacar Coulibaly, Madjou Sacko, Oumou Niaré, Isabelle Morlais, Sekou F Traoré, Kenneth D Vernick, Brian P Lazzaro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3050937?pdf=render

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http://europepmc.org/articles/PMC3050937?pdf=render

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