Concentration-dependent polymorphism of insulin amyloid fibrils

Protein aggregation into highly structured fibrils has long been associated with several neurodegenerative disorders, such as Alzheimer’s or Parkinson’s disease. Polymorphism of amyloid fibrils increases the complexity of disease mechanisms and may be one of the reasons for the slow progress in drug...

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Bibliographic Details
Main Authors: Andrius Sakalauskas, Mantas Ziaunys, Vytautas Smirnovas
Format: Article
Language:English
Published: PeerJ Inc. 2019-12-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/8208.pdf