MiR-30c/PGC-1β protects against diabetic cardiomyopathy via PPARα

Abstract Background Metabolic abnormalities have been implicated as a causal event in diabetic cardiomyopathy (DCM). However, the mechanisms underlying cardiac metabolic disorder in DCM were not fully understood. Results Db/db mice, palmitate treated H9c2 cells and primary neonatal rat cardiomyocyte...

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Bibliographic Details
Main Authors: Zhongwei Yin, Yanru Zhao, Mengying He, Huaping Li, Jiahui Fan, Xiang Nie, Mengwen Yan, Chen Chen, Dao Wen Wang
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Cardiovascular Diabetology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12933-019-0811-7