Understanding the Selectivity Mechanism of the Human Asialoglycoprotein Receptor (ASGP-R) toward Gal- and Man- type Ligands for Predicting Interactions with Exogenous Sugars

A practical approach for addressing the computer simulation of protein-carbohydrate interactions is described here. An articulated computational protocol was setup and validated by checking its ability to predict experimental data, available in theliterature, and concerning the selectivity shown by...

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Bibliographic Details
Main Authors: Emo Chiellini, Federica Chiellini, Anna Maria Bianucci, Laura Murgia, Ilaria Massarelli
Format: Article
Language:English
Published: MDPI AG 2007-01-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/8/1/13/