Binding of Y-P30 to syndecan 2/3 regulates the nuclear localization of CASK.

The survival promoting peptide Y-P30 has documented neuroprotective effects as well as cell survival and neurite outgrowth promoting activity in vitro and in vivo. Previous work has shown that multimerization of the peptide with pleiotrophin (PTN) and subsequent binding to syndecan (SDC) -2 and -3 i...

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Bibliographic Details
Main Authors: Peter Landgraf, Marina Mikhaylova, Tamar Macharadze, Corinna Borutzki, Ana-Claudia Zenclussen, Petra Wahle, Michael R Kreutz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3911912?pdf=render