Gd<sup>3+</sup> Complexes Conjugated to Cyclodextrins: Hydroxyl Functions Influence the Relaxation Properties

Gd<sup>3+</sup> Complexes Conjugated to Cyclodextrins: Hydroxyl Functions Influence the Relaxation Properties

In the search for improvement in the properties of gadolinium-based contrast agents, cyclodextrins (CDs) are interesting hydrophilic scaffolds with high molecular weight. The impact of the hydrophilicity of these systems on the MRI efficacy has been studied using five β-CDs substituted with DOTA or...

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Bibliographic Details
Main Authors: Anais Biscotti, François Estour, Berthe-Sandra Sembo-Backonly, Sébastien Balieu, Michaël Bosco, Cécile Barbot, Agnès Pallier, Éva Tóth, Célia S. Bonnet, Géraldine Gouhier
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Processes
Subjects:
cyclodextrin
gadolinium
contrast agent
magnetic resonance imaging
second hydration sphere
Online Access:https://www.mdpi.com/2227-9717/9/2/269

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https://www.mdpi.com/2227-9717/9/2/269

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