Human iPSC-Derived Endothelial Cells and Microengineered Organ-Chip Enhance Neuronal Development

Summary: Human stem cell-derived models of development and neurodegenerative diseases are challenged by cellular immaturity in vitro. Microengineered organ-on-chip (or Organ-Chip) systems are designed to emulate microvolume cytoarchitecture and enable co-culture of distinct cell types. Brain microva...

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Bibliographic Details
Main Authors: Samuel Sances, Ritchie Ho, Gad Vatine, Dylan West, Alex Laperle, Amanda Meyer, Marlesa Godoy, Paul S. Kay, Berhan Mandefro, Seigo Hatata, Chris Hinojosa, Norman Wen, Dhruv Sareen, Geraldine A. Hamilton, Clive N. Svendsen
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671118301036