Differential regulation of growth-promoting signalling pathways by E-cadherin.

BACKGROUND: Despite the well-documented association between loss of E-cadherin and carcinogenesis, as well as the link between restoration of its expression and suppression of proliferation in carcinoma cells, the ability of E-cadherin to modulate growth-promoting cell signalling in normal epithelia...

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Bibliographic Details
Main Authors: Nikolaos T Georgopoulos, Lisa A Kirkwood, Dawn C Walker, Jennifer Southgate
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2964323?pdf=render