Broadening of neutralization activity to directly block a dominant antibody-driven SARS-coronavirus evolution pathway.

Broadening of neutralization activity to directly block a dominant antibody-driven SARS-coronavirus evolution pathway.

Phylogenetic analyses have provided strong evidence that amino acid changes in spike (S) protein of animal and human SARS coronaviruses (SARS-CoVs) during and between two zoonotic transfers (2002/03 and 2003/04) are the result of positive selection. While several studies support that some amino acid...

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Bibliographic Details
Main Authors: Jianhua Sui, Daniel R Aird, Azaibi Tamin, Akikazu Murakami, Meiying Yan, Anuradha Yammanuru, Huaiqi Jing, Biao Kan, Xin Liu, Quan Zhu, Qing-An Yuan, Gregory P Adams, William J Bellini, Jianguo Xu, Larry J Anderson, Wayne A Marasco
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-11-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18989460/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18989460/?tool=EBI

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