Electrophilic nitro-oleic acid reverses obesity-induced hepatic steatosis

Non-alcoholic fatty liver disease (NAFLD) is linked to obesity and insulin resistance and is the most prevalent chronic liver disease. During the development of obesity and NAFLD, mitochondria adapt to the increased lipid load in hepatocytes by increasing the rate of fatty acid oxidation. In concert...

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Bibliographic Details
Main Authors: Nicholas K.H. Khoo, Marco Fazzari, Dionysios V. Chartoumpekis, Lihua Li, Danielle Aparecida Guimaraes, Gavin E. Arteel, Sruti Shiva, Bruce A. Freeman
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231718312515