Electrophilic nitro-oleic acid reverses obesity-induced hepatic steatosis
Non-alcoholic fatty liver disease (NAFLD) is linked to obesity and insulin resistance and is the most prevalent chronic liver disease. During the development of obesity and NAFLD, mitochondria adapt to the increased lipid load in hepatocytes by increasing the rate of fatty acid oxidation. In concert...
Main Authors: | Nicholas K.H. Khoo, Marco Fazzari, Dionysios V. Chartoumpekis, Lihua Li, Danielle Aparecida Guimaraes, Gavin E. Arteel, Sruti Shiva, Bruce A. Freeman |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-04-01
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Series: | Redox Biology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231718312515 |
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