Characterization of a novel fibroblast growth factor 10 (Fgf10) knock-in mouse line to target mesenchymal progenitors during embryonic development.

Characterization of a novel fibroblast growth factor 10 (Fgf10) knock-in mouse line to target mesenchymal progenitors during embryonic development.

Fibroblast growth factor 10 (Fgf10) is a key regulator of diverse organogenetic programs during mouse development, particularly branching morphogenesis. Fgf10-null mice suffer from lung and limb agenesis as well as cecal and colonic atresia and are thus not viable. To date, the Mlcv1v-nLacZ-24 trans...

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Bibliographic Details
Main Authors: Elie El Agha, Denise Al Alam, Gianni Carraro, Breanne MacKenzie, Kerstin Goth, Stijn P De Langhe, Robert Voswinckel, Mohammad K Hajihosseini, Virender K Rehan, Saverio Bellusci
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3374781?pdf=render

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http://europepmc.org/articles/PMC3374781?pdf=render

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