Roles of PDE1 in Pathological Cardiac Remodeling and Dysfunction

Roles of PDE1 in Pathological Cardiac Remodeling and Dysfunction

Pathological cardiac hypertrophy and dysfunction is a response to various stress stimuli and can result in reduced cardiac output and heart failure. Cyclic nucleotide signaling regulates several cardiac functions including contractility, remodeling, and fibrosis. Cyclic nucleotide phosphodiesterases...

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Bibliographic Details
Main Authors: Si Chen, Walter E. Knight, Chen Yan
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
phosphodiesterases (PDEs)
PDE1
cyclic nucleotide
cardiac hypertrophy
cardiac dysfunction
Online Access:http://www.mdpi.com/2308-3425/5/2/22

Internet

http://www.mdpi.com/2308-3425/5/2/22

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