A Vascular Endothelial Growth Factor-Dependent Sprouting Angiogenesis Assay Based on an In Vitro Human Blood Vessel Model for the Study of Anti-Angiogenic Drugs

A Vascular Endothelial Growth Factor-Dependent Sprouting Angiogenesis Assay Based on an In Vitro Human Blood Vessel Model for the Study of Anti-Angiogenic Drugs

Angiogenesis is the formation of new capillaries from pre-existing blood vessels and participates in proper vasculature development. In pathological conditions such as cancer, abnormal angiogenesis takes place. Angiogenesis is primarily carried out by endothelial cells, the innermost layer of blood...

Full description

Bibliographic Details
Main Authors: Joris Pauty, Ryo Usuba, Irene Gayi Cheng, Louise Hespel, Haruko Takahashi, Keisuke Kato, Masayoshi Kobayashi, Hiroyuki Nakajima, Eujin Lee, Florian Yger, Fabrice Soncin, Yukiko T. Matsunaga
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:EBioMedicine
Subjects:
Angiogenesis inhibitors
DLL4
Human umbilical vein endothelial cell
In vitro 3D model
Microvessel
Notch
Sorafenib
Sprouting angiogenesis
Sunitinib
Vascular endothelial growth factor
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396417304978

Internet

http://www.sciencedirect.com/science/article/pii/S2352396417304978

Similar Items