The relative contributions of infectious and mitotic spread to HTLV-1 persistence.

Human T-lymphotropic virus type-1 (HTLV-1) persists within hosts via infectious spread (de novo infection) and mitotic spread (infected cell proliferation), creating a population structure of multiple clones (infected cell populations with identical genomic proviral integration sites). The relative...

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Bibliographic Details
Main Authors: Daniel J Laydon, Vikram Sunkara, Lies Boelen, Charles R M Bangham, Becca Asquith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-09-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007470