Profiling of IgG antibodies targeting unmodified and corresponding citrullinated autoantigens in a multicenter national cohort of early arthritis in Germany

Profiling of IgG antibodies targeting unmodified and corresponding citrullinated autoantigens in a multicenter national cohort of early arthritis in Germany

Abstract Objective To assess the diagnostic potential of IgG antibodies to citrullinated and corresponding native autoantigens in early arthritis. Methods IgG autoantibodies to 390 distinct unmodified and corresponding in vitro citrullinated recombinant proteins were measured by a multiplex assay in...

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Bibliographic Details
Main Authors: Stefan Vordenbäumen, Ralph Brinks, Patrick Schriek, Angelika Lueking, Jutta G. Richter, Petra Budde, Peter Schulz-Knappe, Hans-Dieter Zucht, Johanna Callhoff, Matthias Schneider
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Arthritis Research & Therapy
Subjects:
Rheumatoid arthritis
Early arthritis
Biomarker
Antibody
Autoantigen
Diagnosis
Online Access:http://link.springer.com/article/10.1186/s13075-020-02252-6

Internet

http://link.springer.com/article/10.1186/s13075-020-02252-6

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