Microwave-assisted ring closure reactions: Synthesis of 8-substituted xanthine derivatives and related pyrimido- and diazepinopurinediones

Background<p>Poly-substituted xanthine derivatives are an important class of compounds in medicinal chemistry. Substitution at the 8-position of the purine ring is generally accessible by ring closure of a carboxamido-substituted uracil precursor. Although several procedures to accomplish this...

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Bibliographic Details
Main Authors: Joachim C. Burbiel, Jörg Hockemeyer, Christa E. Müller
Format: Article
Language:English
Published: Beilstein-Institut 2006-10-01
Series:Beilstein Journal of Organic Chemistry
Online Access:https://doi.org/10.1186/1860-5397-2-20