Prediction of Severity of Drug-Drug Interactions Caused by Enzyme Inhibition and Activation

Prediction of Severity of Drug-Drug Interactions Caused by Enzyme Inhibition and Activation

Drug-drug interactions (DDIs) severity assessment is a crucial problem because polypharmacy is increasingly common in modern medical practice. Many DDIs are caused by alterations of the plasma concentrations of one drug due to another drug inhibiting and/or inducing the metabolism or transporter-med...

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Bibliographic Details
Main Authors: Alexander Dmitriev, Dmitry Filimonov, Alexey Lagunin, Dmitry Karasev, Pavel Pogodin, Anastasiya Rudik, Vladimir Poroikov
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Molecules
Subjects:
drug interactions
ddis
adverse drug reaction
adr
Online Access:https://www.mdpi.com/1420-3049/24/21/3955

Internet

https://www.mdpi.com/1420-3049/24/21/3955

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