Evolution under fluctuating environments explains observed robustness in metabolic networks.

A high level of robustness against gene deletion is observed in many organisms. However, it is still not clear which biochemical features underline this robustness and how these are acquired during evolution. One hypothesis, specific to metabolic networks, is that robustness emerges as a byproduct o...

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Bibliographic Details
Main Authors: Orkun S Soyer, Thomas Pfeiffer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20865149/pdf/?tool=EBI