Perturbation of Interaction Networks for Application to Cancer Therapy

We present a computational approach for studying the effect of potential drug combinations on the protein networks associated with tumor cells. The majority of therapeutics are designed to target single proteins, yet most diseased states are characterized by a combination of many interacting genes a...

Full description

Bibliographic Details
Main Authors: Steven J. M. Jones, Asim S. Siddiqui, Adrian P. Quayle
Format: Article
Language:English
Published: SAGE Publishing 2007-01-01
Series:Cancer Informatics
Subjects:
Online Access:http://la-press.com/article.php?article_id=217