Genetic Abnormalities in Chronic Lymphocytic Leukemia: Where We Are and Where We Go

Chromosomal abnormalities in chronic lymphocytic leukemia (CLL) are detected in up to 80% of patients. Among them, deletions of 11q, 13q, 17p, and trisomy 12 have a known prognostic value and play an important role in CLL pathogenesis and evolution, determining patients outcome and therapeutic strat...

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Bibliographic Details
Main Authors: Anna Puiggros, Gonzalo Blanco, Blanca Espinet
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/435983