Molecular Simplification of Natural Products: Synthesis, Antibacterial Activity, and Molecular Docking Studies of Berberine Open Models

Molecular Simplification of Natural Products: Synthesis, Antibacterial Activity, and Molecular Docking Studies of Berberine Open Models

Berberine, the main bioactive component of many medicinal plants belonging to various genera such as <i>Berberis</i>, <i>Coptis</i>, and <i>Hydrastis</i> is a multifunctional compound. Among the numerous interesting biological properties of berberine is broad anti...

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Bibliographic Details
Main Authors: Gualtiero Milani, Maria Maddalena Cavalluzzi, Roberta Solidoro, Lara Salvagno, Laura Quintieri, Angela Di Somma, Antonio Rosato, Filomena Corbo, Carlo Franchini, Angela Duilio, Leonardo Caputo, Solomon Habtemariam, Giovanni Lentini
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Biomedicines
Subjects:
berberine
molecular simplification
antibacterial activity
FtsZ
‘fragment’
ligand efficiency
Online Access:https://www.mdpi.com/2227-9059/9/5/452

Internet

https://www.mdpi.com/2227-9059/9/5/452

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