Effect of age on brain metabotropic glutamate receptor subtype 5 measured with [18F]FPEB PET

Effect of age on brain metabotropic glutamate receptor subtype 5 measured with [18F]FPEB PET

Objective: Metabotropic glutamate receptor subtype 5 (mGluR5) is integral to the brain glutamatergic system and cognitive function. This study investigated whether aging is associated with decreased brain mGluR5 availability. Methods: Cognitively normal participants (n = 45), aged 18 to 84 years, un...

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Bibliographic Details
Main Authors: Adam P. Mecca, Kelly Rogers, Zachary Jacobs, Julia W. McDonald, Hannah R. Michalak, Nicole DellaGioia, Wenzhen Zhao, Ansel T Hillmer, Nabeel Nabulsi, Keunpoong Lim, Jim Ropchan, Yiyun Huang, David Matuskey, Irina Esterlis, Richard E. Carson, Christopher H. van Dyck
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:NeuroImage
Subjects:
Aging
mGluR5
Glutamate receptor
[18F]FPEB, PET
Online Access:http://www.sciencedirect.com/science/article/pii/S1053811921004948

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http://www.sciencedirect.com/science/article/pii/S1053811921004948

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