Development of an optimized and scalable method for isolation of umbilical cord blood‐derived small extracellular vesicles for future clinical use

Development of an optimized and scalable method for isolation of umbilical cord blood‐derived small extracellular vesicles for future clinical use

Abstract Extracellular vesicles (EV) are a promising therapeutic tool in regenerative medicine. These particles were shown to accelerate wound healing, through delivery of regenerative mediators, such as microRNAs. Herein we describe an optimized and upscalable process for the isolation of EV smalle...

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Bibliographic Details
Main Authors: Renato M. S. Cardoso, Silvia C. Rodrigues, Claudia F. Gomes, Filipe V. Duarte, Maryse Romao, Ermelindo C. Leal, Patricia C. Freire, Ricardo Neves, Joana Simões‐Correia
Format: Article
Language:English
Published: Wiley 2021-06-01
Series:Stem Cells Translational Medicine
Subjects:
angiogenesis
cell signaling
cellular therapy
clinical translation
microRNA
stem cells
Online Access:https://doi.org/10.1002/sctm.20-0376

Internet

https://doi.org/10.1002/sctm.20-0376

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