High-throughput multiparametric imaging flow cytometry: toward diffraction-limited sub-cellular detection and monitoring of sub-cellular processes

High-throughput multiparametric imaging flow cytometry: toward diffraction-limited sub-cellular detection and monitoring of sub-cellular processes

Summary: We present a sheathless, microfluidic imaging flow cytometer that incorporates stroboscopic illumination for blur-free fluorescence detection at ultra-high analytical throughput. The imaging platform is capable of multiparametric fluorescence quantification and sub-cellular localization of...

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Bibliographic Details
Main Authors: Gregor Holzner, Bogdan Mateescu, Daniel van Leeuwen, Gea Cereghetti, Reinhard Dechant, Stavros Stavrakis, Andrew deMello
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Cell Reports
Subjects:
flow cytometry
fluorescence imaging
microfluidics
single cell
colocalization
stress granules
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721001388

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http://www.sciencedirect.com/science/article/pii/S2211124721001388

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