Berberine compounds improves hyperglycemia via microbiome mediated colonic TGR5-GLP pathway in db/db mice

Berberine compounds improves hyperglycemia via microbiome mediated colonic TGR5-GLP pathway in db/db mice

Berberine compounds (BC), consisting of berberine (BBR), oryzanol and vitamin B6, have been used to treat diabetes and hyperlipidemia in recent years, but the potential mechanisms under the effects have not been well determined. In this study, we evaluated the effect of BC in db/db mice, and found t...

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Bibliographic Details
Main Authors: Meng Li, Wenjun Zhou, Yanqi Dang, Chunlin Li, Guang Ji, Li Zhang
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Berberine compounds
Hyperglycemia
Gut microbiota
Deoxycholic acid
Takeda G protein-coupled receptor 5
Glucagon-like peptide
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220311458

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http://www.sciencedirect.com/science/article/pii/S0753332220311458

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