Widespread aggregation of mutant VAPB associated with ALS does not cause motor neuron degeneration or modulate mutant SOD1 aggregation and toxicity in mice
<p>Abstract</p> <p>Background</p> <p>A proline-to-serine substitution at position-56 (P56S) of vesicle-associated membrane protein-associated protein B (VAPB) causes a form of dominantly inherited motor neuron disease (MND), including typical and atypical amyotrophic la...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2013-01-01
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Series: | Molecular Neurodegeneration |
Subjects: | |
Online Access: | http://www.molecularneurodegeneration.com/content/8/1/1 |