Cockayne Syndrome Group B (CSB): The Regulatory Framework Governing the Multifunctional Protein and Its Plausible Role in Cancer

Cockayne Syndrome Group B (CSB): The Regulatory Framework Governing the Multifunctional Protein and Its Plausible Role in Cancer

Cockayne syndrome (CS) is a DNA repair syndrome characterized by a broad spectrum of clinical manifestations such as neurodegeneration, premature aging, developmental impairment, photosensitivity and other symptoms. Mutations in Cockayne syndrome protein B (CSB) are present in the vast majority of C...

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Bibliographic Details
Main Authors: Zoi Spyropoulou, Angelos Papaspyropoulos, Nefeli Lagopati, Vassilios Myrianthopoulos, Alexandros G. Georgakilas, Maria Fousteri, Athanassios Kotsinas, Vassilis G. Gorgoulis
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cells
Subjects:
Cockayne syndrome
Cockayne syndrome protein B
CSB
ERCC6
cancer
Cockayne syndrome pathologies
Online Access:https://www.mdpi.com/2073-4409/10/4/866

Internet

https://www.mdpi.com/2073-4409/10/4/866

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