Interactions of pancreatic lipase with bile salts and dodecyl sulfate
Sodium dodecyl sulfate (SDS) binds to pancreatic lipase in a cooperative manner up to about 200 moles/mole of protein. This binding in a rapid and irreversible inactivation of lipase. Bile salts under certain conditions prevent SDS inactivation of lipase when both detergents are present together. Un...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
1976-09-01
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| Series: | Journal of Lipid Research |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S002222752041747X |