Interactions of pancreatic lipase with bile salts and dodecyl sulfate

Sodium dodecyl sulfate (SDS) binds to pancreatic lipase in a cooperative manner up to about 200 moles/mole of protein. This binding in a rapid and irreversible inactivation of lipase. Bile salts under certain conditions prevent SDS inactivation of lipase when both detergents are present together. Un...

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Bibliographic Details
Main Authors: B Borgstrom, J Donnér
Format: Article
Language:English
Published: Elsevier 1976-09-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752041747X

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