Practical strategy to construct anti-osteosarcoma bone substitutes by loading cisplatin into 3D-printed titanium alloy implants using a thermosensitive hydrogel

Practical strategy to construct anti-osteosarcoma bone substitutes by loading cisplatin into 3D-printed titanium alloy implants using a thermosensitive hydrogel

Surgical resection and perioperative adjuvant chemotherapy-based therapies have improved the prognosis of patients with osteosarcoma; however, intraoperative bone defects, local tumour recurrence, and chemotherapy-induced adverse effects still affect the quality of life of patients. Emerging 3D-prin...

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Bibliographic Details
Main Authors: Zehao Jing, Renhua Ni, Jiedong Wang, Xinhong Lin, Daoyang Fan, Qingguang Wei, Teng Zhang, Yufeng Zheng, Hong Cai, Zhongjun Liu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2021-12-01
Series:Bioactive Materials
Subjects:
3D-printed titanium alloy
Orthopaedic implant
Osteosarcoma
Hydrogel
Local chemotherapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X21002267

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http://www.sciencedirect.com/science/article/pii/S2452199X21002267

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