BAFF/APRIL System Is Functional in B-Cell Acute Lymphoblastic Leukemia in a Disease Subtype Manner

BAFF/APRIL System Is Functional in B-Cell Acute Lymphoblastic Leukemia in a Disease Subtype Manner

BAFF, APRIL and their receptors regulate the survival, maturation and homeostasis of mature B-cells. Despite the lack of a functional role of BAFF/APRIL system during normal early B-cell development, previous studies indicated a contribution of these molecules in the pathogenesis of B-lineage acute...

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Bibliographic Details
Main Authors: Eirini Sevdali, Eleni Katsantoni, Cristian R. Smulski, Maria Moschovi, Maria Palassopoulou, Eleni-Nefeli Kolokotsa, Nikoletta Argentou, Nikolaos Giannakoulas, Maria Adamaki, Georgios Vassilopoulos, Sophia Polychronopoulou, Anastasios E. Germenis, Hermann Eibel, Matthaios Speletas
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Oncology
Subjects:
BAFFR
B-ALL
E2A-PBX1
glucocorticoids
apoptosis
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00594/full

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https://www.frontiersin.org/article/10.3389/fonc.2019.00594/full

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