Molecular cytogenetic identification of small supernumerary marker chromosomes using chromosome microarray analysis

Molecular cytogenetic identification of small supernumerary marker chromosomes using chromosome microarray analysis

Abstract Background This study aimed to evaluate the feasibility of chromosomal microarray analysis (CMA) in detecting the origin and structure of small supernumerary marker chromosomes (sSMCs) in prenatal and postnatal cases and to clarify sSMC-related genotype-phenotype correlations. Results Thirt...

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Bibliographic Details
Main Authors: Huili Xue, Hailong Huang, Yan Wang, Gang An, Min Zhang, Liangpu Xu, Yuan Lin
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Molecular Cytogenetics
Subjects:
Small supernumerary marker chromosome
Prenatal diagnosis
Fluorescence in situ hybridization
Chromosome microarray analysis
Copy number variation
Online Access:http://link.springer.com/article/10.1186/s13039-019-0425-5

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http://link.springer.com/article/10.1186/s13039-019-0425-5

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