Accounting for red blood cell accessibility reveals distinct invasion strategies in Plasmodium falciparum strains.

The growth of the malaria parasite Plasmodium falciparum in human blood causes all the symptoms of malaria. To proliferate, non-motile parasites must have access to susceptible red blood cells, which they invade using pairs of parasite ligands and host receptors that define invasion pathways. Parasi...

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Bibliographic Details
Main Authors: Francisco Y Cai, Tiffany M DeSimone, Elsa Hansen, Cameron V Jennings, Amy K Bei, Ambroise D Ahouidi, Souleymane Mboup, Manoj T Duraisingh, Caroline O Buckee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-04-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007702