Development and validation of the method for the detection of glimepiride via derivatization employing N-methyl-N-(trimethylsilyl) trifluoroacetamide using gas chromatography-mass spectrometry

Development and validation of the method for the detection of glimepiride via derivatization employing N-methyl-N-(trimethylsilyl) trifluoroacetamide using gas chromatography-mass spectrometry

Abstract Background Recent advances in the diversified anti-diabetic drugs have appeared in the startling increase in the count of poisoning cases. The epidemics of diabetes mellitus are increasing; hence, the no. of anti-diabetic drug users raised by 42.9%. The use of glimepiride raised to 24%. As...

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Bibliographic Details
Main Authors: Priyanka Verma, Atul Bajaj, R. M. Tripathi, Sudhir K. Shukla, Suman Nagpal
Format: Article
Language:English
Published: SpringerOpen 2021-02-01
Series:Egyptian Journal of Forensic Sciences
Subjects:
Diabetes mellitus
Glimepiride
MSTFA
Derivatization
Gas chromatography-mass spectrometry
Biological matrices
Online Access:https://doi.org/10.1186/s41935-021-00217-7

Internet

https://doi.org/10.1186/s41935-021-00217-7

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