The DEAD-box Protein Rok1 Orchestrates 40S and 60S Ribosome Assembly by Promoting the Release of Rrp5 from Pre-40S Ribosomes to Allow for 60S Maturation.

The DEAD-box Protein Rok1 Orchestrates 40S and 60S Ribosome Assembly by Promoting the Release of Rrp5 from Pre-40S Ribosomes to Allow for 60S Maturation.

DEAD-box proteins are ubiquitous regulators of RNA biology. While commonly dubbed "helicases," their activities also include duplex annealing, adenosine triphosphate (ATP)-dependent RNA binding, and RNA-protein complex remodeling. Rok1, an essential DEAD-box protein, and its cofactor Rrp5...

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Bibliographic Details
Main Authors: Sohail Khoshnevis, Isabel Askenasy, Matthew C Johnson, Maria D Dattolo, Crystal L Young-Erdos, M Elizabeth Stroupe, Katrin Karbstein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-06-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC4900678?pdf=render

Internet

http://europepmc.org/articles/PMC4900678?pdf=render

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