Inflammatory transcriptome profiling of human monocytes exposed acutely to cigarette smoke.

BACKGROUND:Cigarette smoking is responsible for 5 million deaths worldwide each year, and is a major risk factor for cardiovascular and lung diseases. Cigarette smoke contains a complex mixture of over 4000 chemicals containing 10(15) free radicals. Studies show smoke is perceived by cells as an inf...

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Bibliographic Details
Main Authors: William R Wright, Katarzyna Parzych, Damian Crawford, Charles Mein, Jane A Mitchell, Mark J Paul-Clark
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3281820?pdf=render