ICG-001, an Inhibitor of the β-Catenin and cAMP Response Element-Binding Protein Dependent Gene Transcription, Decreases Proliferation but Enhances Migration of Osteosarcoma Cells

ICG-001, an Inhibitor of the β-Catenin and cAMP Response Element-Binding Protein Dependent Gene Transcription, Decreases Proliferation but Enhances Migration of Osteosarcoma Cells

High-grade osteosarcomas are the most frequent malignant bone tumors in the pediatric population, with 150 patients diagnosed every year in France. Osteosarcomas are associated with low survival rates for high risk patients (metastatic and relapsed diseases). Knowing that the canonical Wnt signaling...

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Bibliographic Details
Main Authors: Geoffroy Danieau, Sarah Morice, Sarah Renault, Régis Brion, Kevin Biteau, Jérôme Amiaud, Marie Cadé, Dominique Heymann, Frédéric Lézot, Franck Verrecchia, Françoise Rédini, Bénédicte Brounais-Le Royer
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Pharmaceuticals
Subjects:
osteosarcoma
β-catenin
proliferation
migration
ICG-001
Online Access:https://www.mdpi.com/1424-8247/14/5/421

Internet

https://www.mdpi.com/1424-8247/14/5/421

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