De novo assembly of a young Drosophila Y chromosome using single-molecule sequencing and chromatin conformation capture.
While short-read sequencing technology has resulted in a sharp increase in the number of species with genome assemblies, these assemblies are typically highly fragmented. Repeats pose the largest challenge for reference genome assembly, and pericentromeric regions and the repeat-rich Y chromosome ar...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2018-07-01
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| Series: | PLoS Biology |
| Online Access: | http://europepmc.org/articles/PMC6117089?pdf=render |