The spectrum of biochemical alterations associated with organ dysfunction and inflammatory status and their association with disease outcomes in severe COVID-19: A longitudinal cohort and time-series design study

Background: In patients with severe COVID-19, no data are available on the longitudinal evolution of biochemical abnormalities and their ability to predict disease outcomes. Methods: Using a retrospective, longitudinal cohort study design on consecutive patients with severe COVID-19, we used an exte...

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Main Authors: Abderrahim Oussalah, Stanislas Gleye, Isabelle Clerc Urmes, Elodie Laugel, Françoise Barbé, Sophie Orlowski, Catherine Malaplate, Isabelle Aimone-Gastin, Beatrice Maatem Caillierez, Marc Merten, Elise Jeannesson, Raphaël Kormann, Jean-Luc Olivier, Rosa-Maria Rodriguez-Guéant, Farès Namour, Sybille Bevilacqua, Nathalie Thilly, Marie-Reine Losser, Antoine Kimmoun, Luc Frimat, Bruno Levy, Sébastien Gibot, Evelyne Schvoerer, Jean-Louis Guéant
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:EClinicalMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2589537020302984