Effects and Mechanism of Nano-Copper Exposure on Hepatic Cytochrome P450 Enzymes in Rats

Effects and Mechanism of Nano-Copper Exposure on Hepatic Cytochrome P450 Enzymes in Rats

Although nano-copper is currently used extensively, the adverse effects on liver cytochrome P450 (CYP450) enzymes after oral exposure are not clear. In this study, we determined the effects and mechanisms of action of nano- and micro-copper on the expression and activity of CYP450 enzymes in rat liv...

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Bibliographic Details
Main Authors: Huaqiao Tang, Min Xu, Fei Shi, Gang Ye, Cheng Lv, Jie Luo, Ling Zhao, Yinglun Li
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:International Journal of Molecular Sciences
Subjects:
nano-copper
oral exposure
liver toxicity
CYP450 enzymes
mechanism
Online Access:http://www.mdpi.com/1422-0067/19/7/2140

Internet

http://www.mdpi.com/1422-0067/19/7/2140

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