Intestinal TMEM16A control luminal chloride secretion in a NHERF1 dependent manner

Intestinal TMEM16A control luminal chloride secretion in a NHERF1 dependent manner

TMEM16A (Transmembrane protein 16A or Anoctamin1) is a calcium-activated chloride channel.(CaCC),that exerts critical roles in epithelial secretion. However, its localization, function, and regulation in intestinal chloride (Cl−) secretion remain obscure. Here, we show that TMEM16A protein abundance...

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Bibliographic Details
Main Authors: Tultul Saha, Joydeep Aoun, Mikio Hayashi, Sheikh Irshad Ali, Paramita Sarkar, Prasanta Kumar Bag, Normand Leblanc, Nadia Ameen, Owen M. Woodward, Kazi Mirajul Hoque
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Biochemistry and Biophysics Reports
Subjects:
Ano1
TMEM16A
NHERF1
Intestine
Cystic fibrosis
Secretion
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580821000066

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http://www.sciencedirect.com/science/article/pii/S2405580821000066

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