Ancestry of the Timorese: Age-related macular degeneration associated genotype and allele sharing among human populations from throughout the world

Ancestry of the Timorese: Age-related macular degeneration associated genotype and allele sharing among human populations from throughout the world

We observed that the third leading cause of blindness in the world, age-related macular degeneration (AMD), occurs at a very low documented frequency in a population-based cohort from Timor-Leste. Thus, we determined a complete catalogue of the ancestry of the Timorese by analysis of whole exome ch...

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Bibliographic Details
Main Authors: Margaux A Morrison, Tiago R Magalhaes, Jacqueline eRamke, Silvia E Smith, Sean eEnnis, Claire L Simpson, Laura ePortas, Federico eMurgia, Jeeyun eAhn, Caitlin eDardenne, Katie eMayne, Rosann eRobinson, Denise J Morgan, Garry eBrian, Lucy eLee, Se Joon eWoo, Fani eZacharaki, Evangelia E Tsironi, Joan W Miller, Ivana K Kim, Kyu Hyung ePark, Joan E Bailey-Wilson, Lindsay A Farrer, Dwight eStambolian, Margaret M DeAngelis
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-07-01
Series:Frontiers in Genetics
Subjects:
Epidemiology
Population Genetics
ancestry
age-related macular degeneration
complex disease
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00238/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00238/full

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