Pathogen-Specific T Cell Polyfunctionality Is a Correlate of T Cell Efficacy and Immune Protection.

Pathogen-Specific T Cell Polyfunctionality Is a Correlate of T Cell Efficacy and Immune Protection.

Understanding the factors that delineate the efficacy of T cell responses towards pathogens is crucial for our ability to develop potent therapies against infectious diseases. Multidimensional evaluation of T cell functionality at the single-cell level enables exhaustive analysis of combinatorial fu...

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Bibliographic Details
Main Authors: Anders Boyd, Jorge R Almeida, Patricia A Darrah, Delphine Sauce, Robert A Seder, Victor Appay, Guy Gorochov, Martin Larsen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4457486?pdf=render

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http://europepmc.org/articles/PMC4457486?pdf=render

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