Depletion of Gut Microbiota Impairs Gut Barrier Function and Antiviral Immune Defense in the Liver

Depletion of Gut Microbiota Impairs Gut Barrier Function and Antiviral Immune Defense in the Liver

Commensal gut microbiota protects the immune defense of extra-intestinal organs. Gut microbiota depletion by antibiotics can impair host antiviral immune responses and alter hepatitis B virus (HBV) infection outcomes. However, how gut microbiota modulates antiviral immune response in the liver remai...

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Bibliographic Details
Main Authors: Weina Guo, Xin Zhou, Xiaoran Li, Qingfeng Zhu, Jing Peng, Bin Zhu, Xin Zheng, Yinping Lu, Dongliang Yang, Baoju Wang, Junzhong Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
antibiotic therapy
gut microbiota
translocation
HBV infection
immune defense
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.636803/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.636803/full

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