Abscisic acid induces a transient shift in signaling that enhances NF-κB-mediated parasite killing in the midgut of Anopheles stephensi without reducing lifespan or fecundity

Abscisic acid induces a transient shift in signaling that enhances NF-κB-mediated parasite killing in the midgut of Anopheles stephensi without reducing lifespan or fecundity

Abstract Background Abscisic acid (ABA) is naturally present in mammalian blood and circulating levels can be increased by oral supplementation. We showed previously that oral ABA supplementation in a mouse model of Plasmodium yoelii 17XNL infection reduced parasitemia and gametocytemia, spleen and...

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Bibliographic Details
Main Authors: Elizabeth K. K. Glennon, Brandi K. Torrevillas, Shannon F. Morrissey, Jadrian M. Ejercito, Shirley Luckhart
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Parasites & Vectors
Subjects:
Plasmodium falciparum
Anopheles stephensi
Abscisic acid
TAK1
Nitric oxide
Lifespan
Online Access:http://link.springer.com/article/10.1186/s13071-017-2276-4

Internet

http://link.springer.com/article/10.1186/s13071-017-2276-4

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