Angiotensin II may mediate apoptosis via AT1-receptors in the rat cardiac conduction system

Introduction Apoptosis and angiotensin II (Ang II) have been suggested as possible causes of arrhythmias. In addition, Ang II via Ang II type I (AT1-) receptors, has been demonstrated to induce cardiomyocyte apoptosis. The transgenic m(Ren-2)27 (TG) rat carries the additional Ren-2 gene, the express...

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Bibliographic Details
Main Authors: Uraporn Vongvatcharanon, Surapong Vongvatcharanon, Nisaudah Radenahmad, Pornpimol Kirirat, Pranom Intasaro, Prasert Sobhon, Terry Parker
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2004-09-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.3317/jraas.2004.030