Wnt Signaling in Cancer Stem Cell Biology

Aberrant regulation of Wnt signaling is a common theme seen across many tumor types. Decades of research have unraveled the epigenetic and genetic alterations that result in elevated Wnt pathway activity. More recently, it has become apparent that Wnt signaling levels identify stem-like tumor cells...

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Bibliographic Details
Main Authors: Felipe de Sousa e Melo, Louis Vermeulen
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/8/7/60