Rapamycin ameliorates experimental autoimmune uveoretinitis by inhibiting Th1/Th2/Th17 cells and upregulating CD4+CD25+ Foxp3 regulatory T cells

<b>AIM:</b>To determine the effects of rapamycin on experimental autoimmune uveoretinitis (EAU) and investigate of role of rapamycin on T cell subsets in the disease. <b>METHODS</b>:EAU was induced in rats using peptides 1169 to 1191 of the interphotoreceptor binding protein...

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Bibliographic Details
Main Authors: Li-Fei Yuan, Guang-Da Li, Xin-Jun Ren, Hong Nian, Xiao-Rong Li, Xiao-Min Zhang
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2015-08-01
Series:International Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.cn/en_publish/2015/4/20150403.pdf