Yolk sac macrophage progenitors traffic to the embryo during defined stages of development

Yolk sac macrophage progenitors traffic to the embryo during defined stages of development

Tissue-resident macrophages are derived from yolk sac progenitors but how and when these progenitors enter is unclear. Here the authors use fate mapping and intravital microscopy to track the movement of resident macrophage precursors from the yolk sac to fetal tissues during development.

Bibliographic Details
Main Authors: C. Stremmel, R. Schuchert, F. Wagner, R. Thaler, T. Weinberger, R. Pick, E. Mass, H. C. Ishikawa-Ankerhold, A. Margraf, S. Hutter, R. Vagnozzi, S. Klapproth, J. Frampton, S. Yona, C. Scheiermann, J. D. Molkentin, U. Jeschke, M. Moser, M. Sperandio, S. Massberg, F. Geissmann, C. Schulz
Format: Article
Language:English
Published: Nature Publishing Group 2018-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-02492-2

Internet

https://doi.org/10.1038/s41467-017-02492-2

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